KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EDC3
All Species:
32.42
Human Site:
T388
Identified Species:
64.85
UniProt:
Q96F86
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96F86
NP_001135915.1
508
56078
T388
E
L
S
L
F
S
K
T
Q
G
Q
Q
V
S
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001097687
287
31155
M184
S
G
L
K
N
G
Q
M
K
N
K
D
D
E
C
Dog
Lupus familis
XP_867080
508
56081
T388
E
L
S
L
F
S
K
T
Q
G
Q
Q
V
S
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2D3
508
55939
T388
E
L
S
L
F
S
K
T
Q
G
Q
Q
V
S
S
Rat
Rattus norvegicus
XP_001072079
506
55875
T386
E
L
S
L
F
S
K
T
Q
G
Q
Q
V
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZLS2
506
56018
T386
E
L
N
L
F
S
S
T
Q
G
Q
Q
V
S
S
Frog
Xenopus laevis
Q5XH48
505
55557
T385
E
L
N
L
F
C
Q
T
Q
G
K
Q
V
S
S
Zebra Danio
Brachydanio rerio
Q502M5
507
54834
T387
E
L
A
L
F
G
K
T
G
G
R
L
V
S
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVI2
680
73397
S525
A
K
L
L
E
Q
N
S
S
S
P
E
I
S
L
Honey Bee
Apis mellifera
XP_392618
616
68864
T501
E
L
S
L
Y
K
L
T
G
N
K
V
E
T
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787406
618
67525
T498
E
I
D
L
F
D
V
T
D
G
V
K
L
Q
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39998
551
61322
K395
K
Q
T
D
I
Y
K
K
C
G
G
K
I
V
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
53.5
96.4
N.A.
95.6
95.8
N.A.
N.A.
88.3
75.1
68.9
N.A.
26.9
30.3
N.A.
35.2
Protein Similarity:
100
N.A.
55.3
98.2
N.A.
97.8
98
N.A.
N.A.
94
85.4
80.3
N.A.
45.2
47
N.A.
51.6
P-Site Identity:
100
N.A.
0
93.3
N.A.
100
100
N.A.
N.A.
86.6
73.3
60
N.A.
13.3
33.3
N.A.
40
P-Site Similarity:
100
N.A.
20
100
N.A.
100
100
N.A.
N.A.
93.3
93.3
80
N.A.
33.3
53.3
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
39.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
9
0
0
9
0
0
0
0
0
9
% C
% Asp:
0
0
9
9
0
9
0
0
9
0
0
9
9
0
0
% D
% Glu:
75
0
0
0
9
0
0
0
0
0
0
9
9
9
0
% E
% Phe:
0
0
0
0
67
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
0
0
0
17
0
0
17
75
9
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
0
9
0
0
0
0
0
0
0
17
0
0
% I
% Lys:
9
9
0
9
0
9
50
9
9
0
25
17
0
0
9
% K
% Leu:
0
67
17
84
0
0
9
0
0
0
0
9
9
0
9
% L
% Met:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% M
% Asn:
0
0
17
0
9
0
9
0
0
17
0
0
0
0
25
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% P
% Gln:
0
9
0
0
0
9
17
0
50
0
42
50
0
9
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% R
% Ser:
9
0
42
0
0
42
9
9
9
9
0
0
0
67
50
% S
% Thr:
0
0
9
0
0
0
0
75
0
0
0
0
0
9
0
% T
% Val:
0
0
0
0
0
0
9
0
0
0
9
9
59
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
9
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _